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As a professional musician and someone who works for a prominent Japanese electronic musical instrument company, I’m going to have to disagree.
Thunderbolt provides all the low latency of a PCIe interface with none of the drawbacks. I use an Antelope Zen Tour in my home studio and it is just amazing.
The systems I designed for work though use RME PCIe cards, but those systems aren’t in the hobbyist space.
Nah, 🏴☠️